A6VF45

PR
Gene name
yidC
Protein name
Membrane protein insertase YidC
Names
Foldase YidC, Membrane integrase YidC, Membrane protein YidC
Species
Pseudomonas aeruginosa (strain PA7)
KEGG Pathway
pap:PSPA7_6369
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

9-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6VF45

Entry ID Method Resolution Chain Position Source
AF-A6VF45-F1 Predicted AlphaFoldDB

No variants for A6VF45

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A6VF45

No associated diseases with A6VF45

3 regional properties for A6VF45

Type Name Position InterPro Accession
domain Membrane insertase YidC, N-terminal 4 - 389 IPR028053
domain Membrane insertase YidC/Oxa/ALB, C-terminal 390 - 569 IPR028055
domain Membrane insertase YidC/ALB, C-terminal 392 - 569 IPR047196

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
membrane insertase activity Binds transmembrane domain-containing proteins and mediates their integration into a membrane.

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIQRSILIV ALAVVSYLLV LQWNKDYGQP ELPAASASMN TTQGLPDTPS AAGTSSDVPT
70 80 90 100 110 120
AQSGAAGSEA ADKPVAVSDK LIQVKTDVLD LAIDPRGGDI VQLGLLQYPR RLDRPDVPFP
130 140 150 160 170 180
LFDNGRERTY LAQSGLTGAD GPDASSAGRP LFHSAQGSYQ LADGQNELVV DLSFSRDGVN
190 200 210 220 230 240
YIKRFTFHRG LKADCSDKEK AQKKIECINE NAYQVGVSYL IDNQSGKTWS GNLFAQLKRD
250 260 270 280 290 300
GSADPSSTTA TGVSTYLGAA VWTPDSPYKK ISTKDMDKEQ FKESVQGGWV AWLQHYFVTA
310 320 330 340 350 360
WVPTKGEQHQ VMTRKDGQGN YIVGFTGPTL SVPAGGKVET DLTLYAGPKL QKHLKELSPG
370 380 390 400 410 420
LELTVDYGFL WFIAQPIFWL LQHIHSLIGN WGWSIIALTV LIKLAFFPLS AASYRSMARM
430 440 450 460 470 480
RAVSPKMQAI KEQHGDDRQK MSQAMMELYK KEKINPLGGC LPILVQMPVF LSLYWVLLES
490 500 510 520 530 540
VEMRQAPWLG WITDLSVKDP FFILPIVMGG TMLIQQMLNP TPPDPMQAKV MKLMPIIFTF
550 560 570
FFLWFPAGLV LYWVVNNVLS IAQQWYITRK IEAAAKTA