Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for A6NK02
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-A6NK02-F1 | Predicted | AlphaFoldDB |
399 variants for A6NK02
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs770178549 CA3128561 |
2 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs1388837247 CA442025551 |
4 | A>V | No |
ClinGen gnomAD |
|
|
rs1390837724 CA442025560 |
5 | A>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1302642576 CA442025557 |
5 | A>S | No |
ClinGen gnomAD |
|
|
rs903816371 CA109717978 |
6 | A>V | No |
ClinGen Ensembl |
|
|
CA442025593 rs1276843626 |
8 | T>A | No |
ClinGen gnomAD |
|
|
rs1391889609 CA442025596 |
8 | T>N | No |
ClinGen TOPMed |
|
| TCGA novel | 9 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128564 rs771236047 |
9 | G>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128563 rs376399427 |
9 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs764166456 CA3128567 |
13 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128568 rs764166456 |
13 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA442026104 rs1186533675 |
16 | C>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1251426725 CA442026121 |
17 | S>F | No |
ClinGen TOPMed |
|
|
CA3128570 rs761598949 |
18 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs761598949 CA442026127 |
18 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA442026159 rs1162560956 |
20 | L>P | No |
ClinGen gnomAD |
|
|
rs186864883 CA3128572 |
22 | Y>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA442026216 rs1417020891 |
24 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1384941578 CA442026230 |
25 | D>E | No |
ClinGen gnomAD |
|
| TCGA novel | 26 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 27 | V>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs151313377 CA3128576 |
27 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 27 | V>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442026263 rs1300398633 |
28 | T>I | No |
ClinGen gnomAD |
|
|
rs936684224 CA109718110 |
29 | I>V | No |
ClinGen TOPMed |
|
|
rs781704625 CA442026288 |
30 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128578 rs781704625 |
30 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs748699308 CA3128579 |
32 | G>W | No |
ClinGen ExAC |
|
|
rs370996331 CA109718142 |
37 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA TOPMed gnomAD |
|
rs756508893 CA3128580 |
37 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs1485383232 CA442026446 |
39 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs895226700 CA109718146 |
41 | Q>H | No |
ClinGen TOPMed gnomAD |
|
|
rs1008281778 CA442026507 |
42 | Q>P | No |
ClinGen TOPMed |
|
|
rs1008281778 CA109718156 |
42 | Q>R | No |
ClinGen TOPMed |
|
|
CA442026531 rs1249759273 |
43 | S>F | No |
ClinGen TOPMed gnomAD |
|
|
CA442026528 rs1249759273 |
43 | S>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA3128581 rs778228596 |
45 | L>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 45 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1411261756 CA442026594 |
47 | L>V | No |
ClinGen gnomAD |
|
|
CA3128583 rs374418042 |
48 | Q>* | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs774683563 CA3128584 |
50 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1455933680 CA442026668 |
51 | F>L | No |
ClinGen gnomAD |
|
|
CA3128585 rs746011891 |
52 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA442026722 rs1264238052 |
53 | C>* | No |
ClinGen TOPMed |
|
| TCGA novel | 55 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128586 rs376170632 |
57 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA109718202 rs376170632 |
57 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA442026784 rs1235475006 |
57 | R>S | No |
ClinGen TOPMed |
|
|
rs1306509016 CA442026836 |
59 | Q>H | No |
ClinGen gnomAD |
|
|
rs775366470 CA3128587 |
59 | Q>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 59 | Q>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128588 rs761843656 |
61 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA109718212 rs900348254 |
62 | E>Q | No |
ClinGen Ensembl |
|
|
rs1269983240 CA442026905 |
64 | H>N | No |
ClinGen gnomAD |
|
|
rs1226779715 CA442026939 |
66 | R>K | No |
ClinGen TOPMed |
|
|
rs773110565 CA3128590 |
67 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs762709303 CA3128591 |
67 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128592 rs766091198 |
68 | N>K | No |
ClinGen ExAC gnomAD |
|
|
CA109718280 rs1005065400 |
69 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
CA442026994 rs1005065400 |
69 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
rs751195592 CA442027007 |
70 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs751195592 CA3128593 |
70 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
CA3128594 rs766966949 |
71 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs370547974 CA109718288 |
73 | R>G | No |
ClinGen ESP TOPMed |
|
|
CA3128595 rs767016046 |
75 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA3128597 rs374852384 |
77 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA442027168 rs1156757430 |
78 | A>P | No |
ClinGen TOPMed |
|
|
rs1473336111 CA442027172 |
78 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs778119422 CA3128598 |
79 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754268321 CA3128599 |
81 | L>P | No |
ClinGen ExAC gnomAD |
|
|
CA109718335 rs1014619911 |
82 | Q>H | No |
ClinGen Ensembl |
|
|
rs779363323 CA3128601 |
83 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128602 rs746093691 |
84 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA442027311 rs1407834710 |
85 | K>E | No |
ClinGen gnomAD |
|
|
rs772386055 CA3128603 |
85 | K>M | No |
ClinGen ExAC gnomAD |
|
|
CA3128606 rs747040534 |
88 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA442027395 rs1313494180 |
88 | K>N | No |
ClinGen gnomAD |
|
|
CA442027402 rs1210175226 |
89 | R>K | No |
ClinGen gnomAD |
|
|
CA442027450 rs1250480795 |
91 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
rs1250480795 CA442027448 |
91 | Q>E | No |
ClinGen TOPMed gnomAD |
|
|
rs769812979 CA3128607 |
93 | E>* | No |
ClinGen ExAC gnomAD |
|
|
rs1216065777 CA442027490 |
93 | E>G | No |
ClinGen TOPMed |
|
|
rs769812979 CA3128608 |
93 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs769812979 CA442027488 |
93 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA3128609 rs762799213 |
94 | T>N | No |
ClinGen ExAC |
|
|
CA442027564 rs1252996827 |
98 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs1207219001 CA442027583 |
99 | K>E | No |
ClinGen TOPMed |
|
|
CA3128611 rs774063173 |
100 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759220892 CA3128612 |
102 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
CA442027665 rs1560915899 |
103 | P>S | No |
ClinGen Ensembl |
|
|
CA442027687 rs1371203484 |
104 | L>P | No |
ClinGen gnomAD |
|
|
rs367912503 CA3128614 |
105 | S>N | No |
ClinGen ESP ExAC gnomAD |
|
|
CA3128616 rs760074535 |
106 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128618 rs531259372 |
110 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 111 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442027817 rs1369641828 |
111 | D>V | No |
ClinGen gnomAD |
|
| TCGA novel | 112 | L>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA109718525 rs969550208 |
113 | M>I | No |
ClinGen Ensembl |
|
|
rs541017397 CA3128619 |
113 | M>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs541017397 CA3128620 |
113 | M>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA442027859 rs1273305067 |
114 | V>M | No |
ClinGen gnomAD |
|
|
rs750765544 CA3128621 |
115 | L>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA442027899 rs1206891938 |
116 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA3128622 rs547991162 |
117 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 118 | L>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1055566647 CA109718578 |
122 | P>H | No |
ClinGen TOPMed gnomAD |
|
|
CA442028005 rs1055566647 |
122 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs936649466 CA109718575 |
122 | P>S | No |
ClinGen TOPMed |
|
|
CA3128625 rs747177124 |
124 | D>E | No |
ClinGen ExAC |
|
|
rs1388402922 CA442028051 |
125 | H>N | No |
ClinGen gnomAD |
|
|
rs1451362903 CA442028073 |
126 | Q>* | No |
ClinGen gnomAD |
|
|
rs1404415699 CA442028094 |
127 | G>D | No |
ClinGen gnomAD |
|
|
rs768600456 CA3128626 |
128 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs145331625 CA3128627 |
130 | V>E | No |
ClinGen 1000Genomes ExAC |
|
|
CA3128628 rs561589234 |
131 | R>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128629 rs373670868 |
132 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs771799408 CA3128632 |
133 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA3128631 rs759306703 |
133 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128630 rs368660880 |
133 | I>V | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1229944347 CA442028205 |
134 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA442028256 rs775002122 |
137 | A>S | No |
ClinGen ExAC gnomAD |
|
|
rs775002122 CA3128633 |
137 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs377139648 CA109718605 |
138 | I>F | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs1052837970 CA109718610 |
139 | H>R | No |
ClinGen Ensembl |
|
|
CA442028305 rs1292480900 |
140 | Y>N | No |
ClinGen gnomAD |
|
|
CA109718615 rs944089379 |
141 | R>S | No |
ClinGen gnomAD |
|
|
rs548680988 CA3128636 |
142 | K>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs372284578 CA3128637 |
146 | S>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs765815347 CA3128638 |
146 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs17045931 CA3128640 |
147 | Y>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA442028456 rs1579191391 |
149 | Q>E | No |
ClinGen Ensembl |
|
|
CA3128641 rs766677979 |
150 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs755165885 CA3128644 |
152 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA3128645 rs765660639 |
153 | K>R | No |
ClinGen ExAC gnomAD |
|
| rs757192242 | 153 | K>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442028574 rs1436729033 |
155 | L>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA442028635 rs1364322845 |
159 | Q>K | No |
ClinGen TOPMed |
|
|
CA442028664 rs1294062035 |
161 | L>* | No |
ClinGen gnomAD |
|
|
CA3128647 rs757236650 |
163 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128648 rs778793502 |
164 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128649 rs369160867 |
164 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA109718715 rs752810394 |
165 | Q>P | No |
ClinGen Ensembl |
|
|
CA3128650 rs771751908 |
168 | K>N | No |
ClinGen ExAC TOPMed |
|
|
CA442028781 rs1357521577 |
168 | K>Q | No |
ClinGen gnomAD |
|
|
CA3128651 rs775298220 |
169 | P>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 169 | P>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA109718755 rs777931709 |
172 | L>M | No |
ClinGen ExAC gnomAD |
|
|
rs954473014 CA109718760 |
172 | L>R | No |
ClinGen TOPMed |
|
|
rs1255564612 CA442028904 |
173 | R>G | No |
ClinGen gnomAD |
|
|
rs776328236 CA3128654 |
175 | M>V | No |
ClinGen ExAC |
|
|
CA109718773 rs750797794 |
176 | V>M | No |
ClinGen gnomAD |
|
|
rs1189908477 CA442029013 |
177 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
rs761374562 CA3128656 |
179 | Q>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128658 rs552543407 |
182 | E>K | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 183 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128659 rs376157880 |
184 | S>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs967163447 CA109718825 |
186 | E>A | No |
ClinGen TOPMed |
|
|
CA442029278 rs766661204 |
188 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA3128661 rs747153360 |
189 | H>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1242082166 CA442029303 |
190 | L>F | No |
ClinGen gnomAD |
|
|
rs1335831642 CA442029309 |
190 | L>P | No |
ClinGen gnomAD |
|
|
CA109718837 rs369928647 |
191 | N>I | No |
ClinGen ESP TOPMed |
|
|
CA3128662 rs755181199 |
192 | Q>H | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 195 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs767707006 CA3128663 |
196 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128664 rs373384813 |
196 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs990825448 CA109718878 |
198 | Q>H | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 202 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1202215674 CA442029641 |
204 | R>T | No |
ClinGen gnomAD |
|
|
rs1216255080 CA442029749 |
209 | E>A | No |
ClinGen TOPMed |
|
|
rs778881327 CA3128667 |
210 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs745818525 CA3128668 |
210 | K>T | No |
ClinGen ExAC gnomAD |
|
|
rs1473425499 CA442029810 |
211 | D>G | No |
ClinGen gnomAD |
|
|
CA442029888 rs1340004247 |
215 | K>E | No |
ClinGen TOPMed |
|
|
CA109718925 rs916541796 |
215 | K>N | No |
ClinGen TOPMed gnomAD |
|
|
CA442029936 rs1173810827 |
217 | S>I | No |
ClinGen gnomAD |
|
|
rs758315366 CA3128670 |
217 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA442029987 rs1375464211 |
219 | N>D | No |
ClinGen gnomAD |
|
|
CA442030003 rs1428713959 |
220 | I>V | No |
ClinGen gnomAD |
|
|
CA3128671 rs779734168 |
221 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1313087261 CA442030058 |
223 | F>L | No |
ClinGen TOPMed |
|
|
CA442030065 rs1408883207 |
224 | S>A | No |
ClinGen TOPMed |
|
|
CA442030073 rs1410804515 |
224 | S>L | No |
ClinGen gnomAD |
|
|
rs768230533 CA109718954 |
227 | S>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768230533 CA3128673 |
227 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1412078487 CA442030136 |
228 | A>D | No |
ClinGen TOPMed |
|
|
rs747715181 CA3128675 |
229 | T>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747715181 CA442030155 |
229 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128677 rs146517052 |
232 | S>N | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA442030215 rs1474444424 |
232 | S>R | No |
ClinGen TOPMed |
|
|
CA442030229 rs1560916144 |
233 | Q>H | No |
ClinGen Ensembl |
|
|
CA3128678 rs535317076 |
233 | Q>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1266661258 CA442030306 |
238 | V>A | No |
ClinGen gnomAD |
|
|
CA3128680 rs774630283 |
239 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 242 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442030359 rs1579191530 |
242 | E>K | No |
ClinGen Ensembl |
|
|
CA3128681 rs759916417 |
243 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1395195529 CA442030441 |
246 | L>P | No |
ClinGen gnomAD |
|
|
CA3128682 rs767796818 |
248 | L>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 255 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128687 rs758316683 |
257 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA442030634 rs758316683 |
257 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA442030645 rs1226582512 |
258 | S>P | No |
ClinGen TOPMed |
|
|
rs1364571735 CA442030704 |
261 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA3128688 rs780009334 |
262 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs773394756 CA109719054 |
262 | S>N | No |
ClinGen Ensembl |
|
|
rs1300145400 CA442030740 |
263 | S>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1244266491 CA442030789 |
265 | S>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1244266491 CA442030792 |
265 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs751376334 CA3128689 |
265 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs1487362227 CA442030866 |
269 | I>L | No |
ClinGen gnomAD |
|
|
rs912522635 CA109719082 |
269 | I>S | No |
ClinGen Ensembl |
|
|
rs1487362227 CA442030867 |
269 | I>V | No |
ClinGen gnomAD |
|
|
rs944033872 CA109719085 |
270 | H>R | No |
ClinGen Ensembl |
|
|
CA442030969 rs1211588685 |
273 | R>S | No |
ClinGen TOPMed gnomAD |
|
|
rs536599015 CA442030990 |
274 | D>E | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs769526884 CA3128693 |
275 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA3128694 rs777451252 |
276 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1391692694 CA442031041 |
277 | S>G | No |
ClinGen gnomAD |
|
|
CA442031046 rs1428758954 |
277 | S>N | No |
ClinGen gnomAD |
|
| TCGA novel | 279 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1560916218 CA442031116 |
280 | P>L | No |
ClinGen Ensembl |
|
|
rs890093879 CA109719099 |
281 | Q>P | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 282 | Y>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442031157 rs1579191601 |
282 | Y>C | No |
ClinGen Ensembl |
|
|
CA3128696 rs771384214 |
282 | Y>D | No |
ClinGen ExAC gnomAD |
|
|
CA3128697 rs149085143 |
283 | S>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1388506035 CA442031187 |
284 | A>T | No |
ClinGen gnomAD |
|
|
rs1433071782 CA442031195 |
284 | A>V | No |
ClinGen gnomAD |
|
|
rs1362671192 CA442031216 |
285 | L>P | No |
ClinGen gnomAD |
|
|
rs760909130 CA3128701 |
286 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA442031234 rs374447273 |
286 | Q>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs374447273 CA3128700 |
286 | Q>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA442031260 rs764278139 |
287 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs764278139 CA3128702 |
287 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1304033698 CA442031295 |
289 | I>K | No |
ClinGen gnomAD |
|
|
rs559713087 CA109719182 |
289 | I>V | No |
ClinGen 1000Genomes gnomAD |
|
|
rs1328377849 CA442031320 |
290 | K>R | No |
ClinGen gnomAD |
|
|
CA442031334 rs1178970221 |
291 | K>E | No |
ClinGen TOPMed |
|
|
rs1325091097 CA442031354 |
292 | F>I | No |
ClinGen gnomAD |
|
|
rs1325091097 CA442031357 |
292 | F>L | No |
ClinGen gnomAD |
|
| TCGA novel | 292 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442031678 rs1180946591 |
304 | H>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA442031665 rs1211737100 |
304 | H>Y | No |
ClinGen TOPMed |
|
| TCGA novel | 305 | P>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1262155937 CA442031731 |
306 | N>K | No |
ClinGen gnomAD |
|
|
rs1253616318 CA442031744 |
307 | L>Q | No |
ClinGen gnomAD |
|
|
CA442031771 rs1273517409 |
308 | I>T | No |
ClinGen TOPMed |
|
|
CA3128706 rs751525257 |
309 | V>G | No |
ClinGen ExAC gnomAD |
|
|
CA3128705 rs766282384 |
309 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA3128707 rs754892682 |
310 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA109719213 rs370178383 |
311 | E>D | No |
ClinGen ESP |
|
|
CA442031905 rs1456118149 |
312 | D>N | No |
ClinGen gnomAD |
|
|
CA442031908 rs1456118149 |
312 | D>Y | No |
ClinGen gnomAD |
|
|
CA442031963 rs1161953854 |
314 | K>Q | No |
ClinGen gnomAD |
|
|
CA442031974 rs1326596310 |
314 | K>T | No |
ClinGen TOPMed |
|
|
rs202127759 CA3128709 |
315 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs202127759 CA442031999 |
315 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs752495138 CA3128710 |
315 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752495138 CA442032010 |
315 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs202127759 CA442031996 |
315 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 315 | R>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1272644662 CA442032086 |
317 | R>I | No |
ClinGen TOPMed |
|
| TCGA novel | 317 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128711 rs755883701 |
318 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs777452935 CA3128712 |
319 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1326945706 CA442032175 |
320 | K>E | No |
ClinGen TOPMed |
|
|
rs866448316 CA109719277 |
320 | K>R | No |
ClinGen Ensembl |
|
|
rs1349574030 CA442032224 |
321 | R>I | No |
ClinGen gnomAD |
|
|
CA3128714 rs574658709 |
321 | R>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 322 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs368403192 CA3128716 |
323 | Q>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA3128718 rs118166729 |
325 | V>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs118166729 CA3128717 |
325 | V>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs118166729 CA3128719 |
325 | V>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3128721 rs747342328 |
326 | P>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1579191699 CA442032444 |
327 | G>R | No |
ClinGen Ensembl |
|
|
rs368160435 CA3128722 |
328 | F>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA442032484 rs1185036943 |
328 | F>Y | No |
ClinGen gnomAD |
|
|
CA109719319 rs1013253717 |
329 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1023327936 CA109719323 |
330 | K>E | No |
ClinGen gnomAD |
|
|
rs776897796 CA3128723 |
331 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 331 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761879264 CA3128724 |
331 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA442032596 rs747701595 |
332 | F>L | No |
ClinGen gnomAD |
|
|
rs531029859 CA3128725 |
332 | F>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs747701595 CA109719333 |
332 | F>V | No |
ClinGen gnomAD |
|
|
rs1407741924 CA442032668 |
334 | V>F | No |
ClinGen gnomAD |
|
|
CA442032664 rs1407741924 |
334 | V>L | No |
ClinGen gnomAD |
|
|
rs1281253299 CA442032703 |
335 | K>Q | No |
ClinGen gnomAD |
|
|
rs759564772 CA442032745 |
336 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs759564772 CA3128727 |
336 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1218188876 CA442032766 |
337 | V>I | No |
ClinGen gnomAD |
|
|
CA3128728 rs767543894 |
338 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA442032804 rs1560916388 |
338 | V>F | No |
ClinGen Ensembl |
|
|
CA3128730 rs774219771 |
339 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs373177133 CA3128731 |
342 | P>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1360306830 CA442032965 |
343 | Y>S | No |
ClinGen TOPMed |
|
| TCGA novel | 350 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 350 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128734 rs778516952 |
353 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA442033381 rs1358805788 |
356 | G>R | No |
ClinGen TOPMed |
|
|
CA442033428 rs1427388619 |
357 | D>G | No |
ClinGen gnomAD |
|
|
CA3128735 rs745359039 |
360 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1560916428 CA442033545 |
361 | W>R | No |
ClinGen Ensembl |
|
|
rs1388517151 CA442033641 |
363 | I>M | No |
ClinGen gnomAD |
|
|
rs191329306 CA3128736 |
363 | I>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1427657729 CA442033737 |
366 | C>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1427657729 CA442033736 |
366 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs780532333 CA3128737 |
367 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs1354839473 CA442033778 |
367 | K>R | No |
ClinGen gnomAD |
|
|
CA442033816 rs1263572076 |
368 | D>G | No |
ClinGen TOPMed |
|
|
CA109719395 rs988750747 |
368 | D>Y | No |
ClinGen Ensembl |
|
| TCGA novel | 369 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442033903 rs1291666991 |
371 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs1291666991 CA442033908 |
371 | P>R | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 372 | T>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 372 | T>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs769075905 CA3128739 |
374 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs932186904 CA109719436 |
377 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
rs776792048 CA442034078 |
377 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA3128740 rs776792048 |
377 | P>T | No |
ClinGen ExAC gnomAD |
|
|
rs1227323537 CA442034136 |
379 | S>L | No |
ClinGen TOPMed |
|
|
rs141550654 CA3128742 |
380 | A>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3128741 rs748429572 |
380 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA442034262 rs1451351443 |
382 | Q>* | No |
ClinGen gnomAD |
|
|
rs1051075690 CA109719443 |
382 | Q>H | No |
ClinGen TOPMed |
|
|
rs1316130840 CA442034328 |
383 | E>K | No |
ClinGen gnomAD |
|
|
rs546859833 CA3128743 |
384 | C>F | No |
ClinGen 1000Genomes ExAC |
|
|
CA442034450 rs1220028070 |
385 | W>* | No |
ClinGen gnomAD |
|
|
rs1220028070 CA442034478 |
385 | W>C | No |
ClinGen gnomAD |
|
| TCGA novel | 385 | W>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442034533 rs1255415039 |
387 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
rs763099095 CA3128744 |
388 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs1246482346 CA442034588 |
389 | L>M | No |
ClinGen gnomAD |
|
| TCGA novel | 390 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 391 | D>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442034681 rs1451573037 |
392 | D>N | No |
ClinGen gnomAD |
|
|
CA109719461 rs890719213 |
393 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
CA442034813 rs1419992433 |
394 | Y>C | No |
ClinGen gnomAD |
|
|
rs767631904 CA3128745 |
394 | Y>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775558836 CA3128746 |
395 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128750 rs372390721 |
399 | A>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs756957159 CA3128751 |
401 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA3128752 rs568428229 |
402 | T>N | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 404 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1012761655 CA109719545 |
405 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs931372161 CA109719535 |
405 | L>S | No |
ClinGen Ensembl |
|
|
rs748434893 CA3128759 |
406 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1194230273 CA442035443 |
412 | A>D | No |
ClinGen gnomAD |
|
|
CA3128762 rs112214814 |
412 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA3128763 rs771150020 |
413 | I>V | No |
ClinGen ExAC TOPMed |
|
|
rs373758333 CA3128764 |
414 | G>D | No |
ClinGen ESP ExAC gnomAD |
|
|
CA3128765 rs760697812 |
415 | I>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 418 | D>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA442035633 rs909005641 |
418 | D>N | No |
ClinGen gnomAD |
|
|
CA109719624 rs909005641 |
418 | D>Y | No |
ClinGen gnomAD |
|
|
rs376693859 CA3128767 |
419 | Y>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs376693859 CA442035654 |
419 | Y>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs761508981 CA3128768 |
422 | G>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1560916571 CA442035795 |
424 | I>L | No |
ClinGen Ensembl |
|
|
rs1356357075 CA442035819 |
424 | I>M | No |
ClinGen TOPMed |
|
|
rs537144111 CA3128769 |
425 | S>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs765903059 CA3128772 |
428 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128774 rs755553606 |
429 | M>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs755553606 CA3128775 |
429 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA3128773 rs751016875 |
429 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs753176713 CA3128776 |
431 | E>* | No |
ClinGen ExAC gnomAD |
|
|
rs1166844583 CA442036047 |
431 | E>G | No |
ClinGen TOPMed |
|
| TCGA novel | 433 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1560916607 CA442036522 |
441 | T>N | No |
ClinGen Ensembl |
|
|
CA3128780 rs778228991 |
443 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 443 | T>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs749527622 CA3128781 |
444 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs77235885 CA3128783 |
445 | P>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA442036787 rs1361959244 |
447 | R>Q | No |
ClinGen gnomAD |
|
|
CA3128784 rs745914840 |
447 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA442036818 rs1470914573 |
448 | P>T | No |
ClinGen gnomAD |
|
|
CA3128788 rs775944401 |
449 | Y>* | No |
ClinGen ExAC |
|
|
CA3128789 CA442036931 rs768705789 |
450 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA109719804 rs1032085944 |
450 | F>V | No |
ClinGen Ensembl |
|
|
rs776418732 CA3128790 |
451 | Y>C | No |
ClinGen ExAC |
|
|
CA3128792 rs183550994 |
452 | V>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA3128795 rs553271414 |
454 | P>R | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs762613539 CA3128794 |
454 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751118213 CA3128796 |
455 | D>H | No |
ClinGen ExAC gnomAD |
|
|
rs1338035591 CA442037182 |
457 | Q>K | No |
ClinGen gnomAD |
|
|
rs1240321637 CA442037186 |
457 | Q>P | No |
ClinGen gnomAD |
|
|
rs975654338 CA109719837 |
460 | R>G | No |
ClinGen TOPMed |
|
|
CA442037425 rs1342913365 |
462 | C>R | No |
ClinGen gnomAD |
|
|
rs1485898205 CA442037535 |
464 | G>E | No |
ClinGen gnomAD |
|
|
rs768131798 CA3128798 |
464 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1204166077 CA442037578 |
465 | T>A | No |
ClinGen gnomAD |
|
| TCGA novel | 465 | T>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA3128799 rs753160062 |
465 | T>R | No |
ClinGen ExAC |
|
|
rs756578145 CA3128800 |
468 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA3128802 rs189009355 |
469 | E>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA3128801 rs778315010 |
469 | E>R | No |
ClinGen ExAC gnomAD |
No associated diseases with A6NK02
13 regional properties for A6NK02
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | B-box-type zinc finger | 92 - 133 | IPR000315 |
| domain | Zinc finger, RING-type | 16 - 57 | IPR001841 |
| domain | B30.2/SPRY domain | 276 - 468 | IPR001870 |
| domain | SPRY domain | 346 - 465 | IPR003877 |
| domain | Butyrophylin-like, SPRY domain | 292 - 309 | IPR003879-1 |
| domain | Butyrophylin-like, SPRY domain | 309 - 326 | IPR003879-2 |
| domain | Butyrophylin-like, SPRY domain | 331 - 355 | IPR003879-3 |
| domain | Butyrophylin-like, SPRY domain | 361 - 374 | IPR003879-4 |
| domain | Butyrophylin-like, SPRY domain | 404 - 428 | IPR003879-5 |
| domain | Butyrophylin-like, SPRY domain | 434 - 452 | IPR003879-6 |
| domain | SPRY-associated | 293 - 345 | IPR006574 |
| conserved_site | Zinc finger, RING-type, conserved site | 31 - 40 | IPR017907 |
| domain | TRIM75, PRY/SPRY domain | 276 - 462 | IPR035785 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| spindle | The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ubiquitin protein ligase activity | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. |
| zinc ion binding | Binding to a zinc ion (Zn). |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| female meiosis I | The cell cycle process in which the first meiotic division occurs in the female germline. |
| innate immune response | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. |
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
| regulation of gene expression | Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
13 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9H2S5 | RNF39 | RING finger protein 39 | Homo sapiens (Human) | PR |
| Q86UV7 | TRIM73 | Tripartite motif-containing protein 73 | Homo sapiens (Human) | PR |
| Q86XT4 | TRIM50 | E3 ubiquitin-protein ligase TRIM50 | Homo sapiens (Human) | PR |
| Q6ZMU5 | TRIM72 | Tripartite motif-containing protein 72 | Homo sapiens (Human) | PR |
| Q9UPQ4 | TRIM35 | E3 ubiquitin-protein ligase TRIM35 | Homo sapiens (Human) | PR |
| Q9BZY9 | TRIM31 | E3 ubiquitin-protein ligase TRIM31 | Homo sapiens (Human) | PR |
| Q9C029 | TRIM7 | E3 ubiquitin-protein ligase TRIM7 | Homo sapiens (Human) | PR |
| O15553 | MEFV | Pyrin | Homo sapiens (Human) | SS |
| A6NCK2 | TRIM43B | Tripartite motif-containing protein 43B | Homo sapiens (Human) | PR |
| Q8N9V2 | TRIML1 | Probable E3 ubiquitin-protein ligase TRIML1 | Homo sapiens (Human) | PR |
| P19474 | TRIM21 | E3 ubiquitin-protein ligase TRIM21 | Homo sapiens (Human) | PR |
| Q14142 | TRIM14 | Tripartite motif-containing protein 14 | Homo sapiens (Human) | PR |
| Q5EBN2 | TRIM61 | Putative tripartite motif-containing protein 61 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVAAALTGL | QAEAKCSICL | DYLSDPVTIE | CGHNFCRSCI | QQSWLDLQEL | FPCPVCRHQC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QEGHFRSNTQ | LGRMIEIAKL | LQSTKSNKRK | QEETTLCEKH | NQPLSVFCKE | DLMVLCPLCT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QPPDHQGHHV | RPIEKAAIHY | RKRFCSYIQP | LKKQLADLQK | LISTQSKKPL | ELREMVENQR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QELSSEFEHL | NQFLDREQQA | VLSRLAEEEK | DNQQKLSANI | TAFSNYSATL | KSQLSKVVEL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SELSELELLS | QIKIFYESEN | ESSPSIFSIH | LKRDGCSFPP | QYSALQRIIK | KFKVEIILDP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ETAHPNLIVS | EDKKRVRFTK | RKQKVPGFPK | RFTVKPVVLG | FPYFHSGRHF | WEIEVGDKSE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| WAIGICKDSL | PTKARRPSSA | QQECWRIELQ | DDGYHAPGAF | PTPLLLEVKA | RAIGIFLDYE |
| 430 | 440 | 450 | 460 | ||
| MGEISFYNMA | EKSHICTFTD | TFTGPLRPYF | YVGPDSQPLR | ICTGTVCE |