Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for A2RNS2

Entry ID Method Resolution Chain Position Source
6FI9 X-ray 280 A A/B/C/D/E/F/G/H 2-145 PDB
AF-A2RNS2-F1 Predicted AlphaFoldDB

No variants for A2RNS2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2RNS2

No associated diseases with A2RNS2

6 regional properties for A2RNS2

Type Name Position InterPro Accession
domain PAS domain 119 - 230 IPR000014-1
domain PAS domain 333 - 400 IPR000014-2
domain Protein kinase domain 1059 - 1311 IPR000719
active_site Serine/threonine-protein kinase, active site 1184 - 1196 IPR008271
domain PAS fold 131 - 221 IPR013767
binding_site Protein kinase, ATP binding site 1065 - 1092 IPR017441

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLANQIDQF LGAIMQFAEN KHEILLGECE SNVKLTSTQE HILMILAAEV STNARIAEQL
70 80 90 100 110 120
KISPAAVTKA LKKLQEQELI KSSRATNDER VVLWSLTEKA IPVAKEHAAH HEKTLSTYQE
130 140
LGDKFTDEEQ KVISQFLSVL TEEFR