A2BID7

PR
Gene name
prdm10 (si:ch211-151h10.3, si:dkey-11k4.2)
Protein name
PR domain zinc finger protein 10
Names
PR domain-containing protein 10
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

392-493 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A2BID7

Entry ID Method Resolution Chain Position Source
AF-A2BID7-F1 Predicted AlphaFoldDB

No variants for A2BID7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A2BID7

No associated diseases with A2BID7

12 regional properties for A2BID7

Type Name Position InterPro Accession
domain SET domain 173 - 290 IPR001214
domain Zinc finger C2H2-type 319 - 346 IPR013087-1
domain Zinc finger C2H2-type 500 - 522 IPR013087-2
domain Zinc finger C2H2-type 529 - 556 IPR013087-3
domain Zinc finger C2H2-type 557 - 579 IPR013087-4
domain Zinc finger C2H2-type 585 - 613 IPR013087-5
domain Zinc finger C2H2-type 613 - 640 IPR013087-6
domain Zinc finger C2H2-type 641 - 669 IPR013087-7
domain Zinc finger C2H2-type 696 - 724 IPR013087-8
domain Zinc finger C2H2-type 741 - 769 IPR013087-9
domain Zinc finger C2H2-type 803 - 826 IPR013087-10
domain PRDM10, PR/SET domain 168 - 298 IPR044403

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
metal ion binding Binding to a metal ion.
methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.

3 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9NQV6 PRDM10 PR domain zinc finger protein 10 Homo sapiens (Human) PR
Q3UTQ7 Prdm10 PR domain zinc finger protein 10 Mus musculus (Mouse) PR
10 20 30 40 50 60
MEAKQESSTV WSTASNNDTG NTPQVHFEAG AVAQIVYSGD QSDRTQQQVV YAADGSSYTS
70 80 90 100 110 120
VESAEHTLVY IHPADGTQSQ LAVTNAALPT LTEASSSPLG ATDSTVDSED EEEDNDSEDS
130 140 150 160 170 180
EMDDWEPRAL QPFTPQNLWC EDCNNANPAA CIKHGPLHPI LNRPVMSKAR ASLPLVLYID
190 200 210 220 230 240
RFLGGVFTKR RIPKRTQFGP LEGPLVRQSE LLDTHIHLKL YMLDPEKEGE RAQDLWFDLS
250 260 270 280 290 300
DEERCNWMMF VRPAQNHLEQ NLVAYQYGSD IFYTSIKNIQ PKQELKVWYA ASYAEFVNQK
310 320 330 340 350 360
VHDVTEEERK VLREQEKNWP CYECNRRFMS SEQLQQHLNM HDDKLNLIQR PKSRGRGRGR
370 380 390 400 410 420
KRFGGARRPG RRTKFLCPQT PVESADKTQE LLASVDKLQF EERTDGALNG LKVVEMAAES
430 440 450 460 470 480
METETEDALD PPPIHTESLQ DEEDSVTPPP VTEIPESAKD DLSHTSPIDP HLTPQDMRRA
490 500 510 520 530 540
RRIRNAALKH LFIRKSFRPF KCPQCGKAFR DKEKLEQHMR FHGRDGCRHV CHQCGKGFLS
550 560 570 580 590 600
STSLEDHLVL HSDQRNYSCL FCAESYDRLE LLKVHVGIHM VNGCFLCPSC KKSFTDFIQV
610 620 630 640 650 660
KKHVRSFHSE KVFQCSECDK AFCRPDKLRL HMLRHSDRKD FLCSTCGKQF KRKDKLREHM
670 680 690 700 710 720
QRMHNPEREA KKADRIHRTK ALKQKEPTTD FESFMFKCRL CMMGFRRRGM LVNHLSKRHP
730 740 750 760 770 780
EMRLEEVPEL TLPIIKPNRD YYCQYCDKVY KSASKRKAHI LKNHPGAELP PSIRKLRPAG
790 800 810 820 830 840
PGEPDPMLST HTQLTGTIAT APVCCPHCAK QYSSKTKMVQ HIRKKHPEYQ YNSSSNIQAP
850 860 870 880 890 900
LAATVISSTP AVITTDGTTA EAVVTTDLLT QAMTELSQTL TTDYRTAQGD FQRIQYIPVS
910 920 930 940 950 960
QAGGGLSQPQ HIQLQVVQVA PASSPHSQHS TVDVSQLHDP HSYSQHSIQV QHIQVAEPTA
970 980 990 1000 1010 1020
AVQANAQVSG QPLSPSSQQA AQELSTAQLT PVTLAQQTLQ TSSNQTQGAT QHAYLPSNWN
1030 1040 1050 1060 1070 1080
YRSYPSEIQM MALPHTQYVI AEASTPVTAA VNSSQVKTTH YVISDGQTEL DGKQVSVPST
1090 1100 1110 1120
ATQGHPDPLE QPAGGQQATT QYIITTTTNG AGASEVHITK P